Step Two is expected to take approximately 1 week, or around 40 hours, to complete. Be sure to factor this into your planning, this time estimate assumes all team members are working exclusively on this project.
(UNC, 2025)
Developing a protocol is a critical part of conducting a high-quality review. A protocol is a detailed plan that outlines why and how you are conducting your review. It helps ensure that your methods are transparent, reproducible, and limits bias. In systematic reviews, protocols should follow established standards such as PRISMA-P and are typically registered in platforms like PROSPERO.
To have a thorough plan in place check out:
Having a written protocol not only serves as a physical reference for team members, but also offers several key benefits:
Reduces bias by pre-defining objectives and methods
Promotes rigor and consistency throughout the review
Improves transparency and reproducibility
Avoids duplication by checking if similar reviews are already underway
Facilitates collaboration and keeps the team aligned
Supports publication and strengthens credibility
Clarifies scope with clear inclusion/exclusion criteria
A well-structured protocol should include the following key elements to ensure transparency, consistency, and rigor throughout the review process:
Team members and their roles
Rationale and objectives of the review
Eligibility criteria (inclusion and exclusion)
Databases and search terms (include a full search strategy for at least one database)
Process and tools for screening, quality assessment, and data extraction
Data items to be extracted
Methods for data synthesis and analysis
For systematic reviews, use a structured template like:
Registering your protocol improves transparency and prevents duplication. Popular registries include:
PROSPERO – Free, widely used for health-related systematic reviews
Open Science Framework (OSF) – Free and suitable for various types of reviews
Research Registry – Paid option for multiple study types
INPLASY – International database for review protocols (paid)
Protocols.io – Free platform for collaborative and reproducible protocols