Skip to Main Content

Gibson D. Lewis Library Libguides

Systematic Reviews

Resources for conducting systematic reviews

Step One

Step One: Plan Your Review

Good planning is crucial for creating any high-quality evidence synthesis. When starting a systematic review, rapid review, or any other type, it's important to begin with a clear plan. This involves creating a focused research question, assembling the right team, and clearly defining the scope and goals of the review. Systematic reviews often need a detailed approach and are usually done by a team with various skills. The team typically includes subject experts, a librarian or someone experienced in literature searching, a statistician, and sometimes a project manager to keep everything on track.
 

Key components of planning include:

Formulating a Research Question

The research question is the foundation of your review. A well-defined question helps determine the direction of the search, the inclusion criteria, and the type of evidence needed. It should be specific, focused, and structured in a way that allows for systematic investigation. Using a framework—such as PICO, PICOT, or PEO—can help you break down your question into key components and ensure it’s answerable with existing evidence.

See the frameworks below for help in structuring your question based on your review type.

Developing a Clinical Question with PICO

When looking at topics that surround clinical interventions, PICO is a mnemonic that helps organize a case scenario or research topic into a focused clinical research question. PICO stands for: Population, Intervention, Comparison, and Outcome.

Developing a Non-Clinical Question

To explore questions that are more focused on experiences, perception, or social phenomena rather than on clinical interventions, other structures can help create a concise and answerable research question. These structures are especially helpful with qualitative or mixed-methods research when context and perspective are the most salient.

PICo

PICo is a commonly used framework for developing qualitative research questions, especially those exploring experiences, perceptions, or views. It stands for Population, Interest, and Context. This structure helps researchers create focused, answerable questions by identifying the group being studied, the phenomena or issue of interest, and the setting or context in which it occurs.

PEO

Framework often used for qualitative research and focuses on understanding experiences, perceptions, or phenomena. It stands for Population, Exposure, and Outcome, allowing researchers to explore how a certain exposure or experience affects a specific group and what the resulting outcomes are.

SPICE

SPICE is a framework commonly used in evaluating service delivery, interventions, or policy questions. It stands for Setting, Perspective, Intervention, Comparison, and Evaluation. This tool helps structure questions around how services or interventions are experienced or perceived in real-world contexts.

SPIDER

SPIDER is tailored for qualitative and mixed-methods research. It stands for Sample, Phenomenon of Interest, Design, Evaluation, and Research type. SPIDER helps researchers frame questions to capture more subjective outcomes like attitudes, experiences, or processes.

Assemble a Team and Assign Roles

A good review depends on putting together the right team. At minimum, a systematic review should include at least two reviewers to reduce bias. Depending on the review type and complexity, your team may also include a subject matter expert, a librarian or information specialist for developing and running the search strategy, and a statistician for data analysis. In some cases, a project manager can help coordinate tasks and timelines. Clearly define each team member’s role early in the process to ensure efficiency, accountability, and consistent communication throughout the review.

  • Lead Reviewer / Principal Investigator – Oversees the entire review process and ensures methodological integrity

  • Co-Reviewers – Screen studies, extract data, assess quality, and help resolve disagreements

  • Subject Matter Expert – Offers subject-matter knowledge to direct the formulation of questions and guides the interpretation of findings

  • Librarian / Information Specialist/ Skilled Searcher – Creates and runs comprehensive search strategies across multiple databases

  • Statistician / Data Analyst – Assists with data analysis, meta-analysis, and the interpretation of statistical results

  • Project Manager – Coordinates timelines, tracks progress, and ensures the team stays on schedule

  • Methodologist – Provides guidance on review procedures, such as inclusion/exclusion standards and tools for evaluating quality

Set the Review's Scope, Objectives, and Timeline

Setting clear rules for your review helps keep the project organized and focused. Follow these steps to help your team discuss what the review will cover, what you want to achieve, and the time frame.

  • Define the scope

    • Decide what the review will include and exclude (e.g., population, interventions, outcomes, study types)

  • Establish clear objectives

    • Clearly outline what you want to accomplish. This might be summarizing evidence, finding research gaps, or helping with clinical guidelines

  • Develop a timeline

    • Plan the time needed for each part of the review, from protocol development to final synthesis

    • Consider team's availability, potential delays, and important deadlines

  • Align the team on goals and expectations

    • Ensure everyone knows the scope, main goals, and timeline before starting

Conduct Preliminary Research and Search for Registered Protocols

Before you spend a lot of effort and time on a review, you should explore what as already been accomplished in the research. This helps you refine your question, assess feasibility, and ensure your review adds value to the field.

Why It Matters:

  • Prevents unnecessary duplication of existing reviews

  • Allows you to contribute to what is already known rather than reproducing it

  • Refines your question and search strategy by identifying gaps or saturation in the literature

How to Conduct Preliminary Research:

  • Scan recent literature in databases like PubMed, Embase, CINAHL, or Scopus to see what has already been published

  • Review key journals in your subject area to find related reviews or studies

  • Consult subject experts or librarians for insights into the research landscape

Search Protocol Registries:

Check whether a systematic review or similar project has already been started by searching established protocol registries:

Apply appropriate keywords and filters to check if an overlapping review is already registered or published. If a review with similarity is identified, consider whether yours will provide a different perspective, newer evidence, or a different population or intervention focus.